CHERUBISM – NATURAL HISTORY & REGRESSION
Cherubism: Clinicoradiographic Features, Treatment, and Long Term Follow-Up of 8 Cases. Journal of Oral Maxillofacial Surgery. 65: 517-522, 2007, Silva, Edgard Carvalho; Carvalho, Guilherme Costa; Vieira, Tainab Couto.
This article describes the progression of 8 Brazilian cases of cherubism in females and males from childhood, through adolescence and into adulthood. This article offers good photographs and radiographs of individuals at various stages of disease progression. Using the classical grading system for cherubism, the authors associate different patterns of remission (regression) with the location of the cherubic lesions in the jaws. Typically regression occurs in the mandible before the maxilla. The authors also discuss the nature of surgical interventions.
Cherubism: Long Term Follow-Up of 2 Patients in Whom it Regressed without Treatment, British Journal of Oral and Maxillofacial Surgery. 2006, Silva, Guilherme Costa Carvalho; Gomez Ricardo Santiago; Vieira, Tainah Couto and Silva, Edgard Carvalho.
This article describes the spontaneous remission / regression of cherubism lesions in the adolescence of two boys who were followed between ages 6 and 23 and 6 and 25. The authors provide photographs and radiographs of the individuals pre and post remission, clearly showing the filling in of the fibrous lesions with bone. (These cases are included within Silva 2007.)